Abstract
Birth defects are the leading cause of death in newborns and children up to 5 years of age, as well as a major cause of long-term disability, burdening the individual, family, society, and health systems. Although a large part of the causes of congenital malformations remain unknown, a number of factors, from maternal health surveillance, the mother's lifestyle, medical care throughout pregnancy can be influenced so that the risk of such accidents is diminished. The health system, public health is an important part of this process, the real knowledge of the phenomenon representing the starting point in establishing future interventions and strategies.